top of page
Search

Why Your ADHD Medication May Feel Like It’s “Not Working”

  • Writer: GPW
    GPW
  • Sep 29
  • 2 min read
ree

One of the most common concerns I hear from adults with ADHD is:


“My stimulant isn’t working anymore.”


This can feel frustrating and discouraging, but the truth is, it’s not always as simple as “the medicine stopped working.” True tolerance to ADHD medication is actually less common than people think. More often, life factors, health changes, or even your perception of progress affect how the medication feels.


Below are some reasons this might be happening—and what to keep in mind.




1. Perception vs. Reality



Sometimes it seems like the medication isn’t helping, even though it actually is. Over time, people become more aware of their challenges. That awareness itself can feel discouraging, but it doesn’t mean the medicine stopped working. Looking back at how things were before starting treatment often gives a clearer perspective.




2. Other Mental Health Conditions



If anxiety or depression develops—or was missed in the first evaluation—it can make ADHD symptoms feel worse. Addressing those conditions often helps ADHD medication feel effective again.




3. Caffeine



Energy drinks, pre-workout powders, or too much coffee can interfere with ADHD medications. They can also worsen anxiety in some people.




4. Marijuana



While marijuana may feel helpful in the moment, it often works against ADHD medication. For many, it makes attention, focus, and memory worse.




5. Sleep, Nutrition, and Exercise



If you’re not sleeping well, skipping meals, or avoiding exercise, your medication won’t feel as effective.


  • Prioritize good sleep

  • Eat regular, balanced meals

  • Stay hydrated

  • Move your body



These healthy habits boost the effectiveness of treatment.




6. Lifestyle and Environment



Sometimes the challenge isn’t the medication—it’s the environment. A job or daily routine filled with overwhelming or boring tasks can strain anyone, especially someone with ADHD. Medication helps, but it can’t fully change your circumstances.




7. Medical Issues



Certain health changes—like low vitamin B12, thyroid problems, or anemia—can make ADHD symptoms worse. Routine labs and check-ins with your doctor help rule these out.




8. Long-Term Side Effects of Stimulants (and How to Avoid Them)



Stimulants are generally safe under medical supervision, but long-term use can come with risks. Common side effects include:


  • Appetite suppression & weight loss → Eat balanced meals and don’t skip breakfast.

  • Sleep problems → Take medication earlier in the day and keep a regular sleep schedule.

  • Increased heart rate or blood pressure → Monitor regularly and follow up with your provider.

  • Mood changes or irritability → Often improved by adjusting dose, timing, or formulation.

  • Potential for misuse → Always take as prescribed and store safely.



👉 The best way to reduce risks is by following your provider’s guidance, scheduling routine check-ups, and using the lowest effective dose.




The Bottom Line



If your ADHD medication feels like it’s “not working,” it doesn’t always mean you need a higher dose. It could be other factors in your health, habits, or environment.


If you’re worried about long-term side effects, know that most can be managed—or even avoided—with proper monitoring and lifestyle adjustments.


The best next step? Talk with your provider before making changes. Together, you can figure out whether it’s truly tolerance—or if something else is getting in the way of your treatment working its best.



 
 
 
bottom of page